Encouraging First-in-Human Results for a Promising HIV Vaccine
Researchers used a customized nanoparticle (top left) to learn more about guiding the immune system to mount a desired robust response, the type needed for an effective HIV vaccine. Credit: Donny...
View ArticleMapping Immune Cell “Neighborhoods” in Psoriasis to Understand its Course
Researchers mapped immune cell “neighborhoods” in the skin of people with psoriasis compared to the healthy skin of people without psoriasis to learn more about the disease course and why it comes...
View ArticleImmune Resilience is Key to a Long and Healthy Life
Caption: A new measure of immunity called immune resilience is helping researchers find clues as to why some people remain healthier even in the face of varied inflammatory stressors. Credit: Modified...
View ArticleChanges in Human Microbiome Precede Alzheimer’s Cognitive Declines
Caption: The human gut teems with bacteria and other microbes. They contribute to our health but also influence our susceptibility to certain diseases, including Alzheimer’s disease. Credit: Donny...
View ArticlePlans for New Cancer Center in Kansas
It was a pleasure to be in Kansas City and join U. S. Senator Jerry Moran of Kansas to celebrate progress toward the construction of a new building for the University of Kansas Cancer Center. The...
View ArticleVisit the New NIH Virtual Tour
Happy Fourth of July! Before everyone heads out to celebrate the holiday with their family and friends, I want to share this brief video with you. It’s an introduction to the brand-new NIH Virtual...
View ArticleUnderstanding Causes of Devastating Neurodegenerative Condition Affecting...
Researchers studied the lack of functional CLN3 protein, which underlies Batten disease. They found lack of the protein leads to a breakdown of the M6PR receptor (green) in the lysosomes and...
View ArticleCryo-EM Scores Again
Caption: Researchers recently published the near-atomic structure of the neuronal pore CALHMI. Credit: Donny Bliss, NIH Human neurons are long, spindly structures, but if you could zoom in on their...
View Article3D Animation Captures Viral Infection in Action
With the summer holiday season now in full swing, the blog will also swing into its annual August series. For most of the month, I will share with you just a small sampling of the colorful videos and...
View ArticleHow Neurons Make Connections
Credit: Emily Heckman, Doe Lab, University of Oregon, Eugene For many people, they are tiny pests. These fruit flies that sometimes hover over a bowl of peaches or a bunch of bananas. But for a...
View ArticleNIH Welcomes Visitors from OSTP
It was my pleasure to welcome Arati Prabhakar (2nd from right) during her visit to NIH on August 3. Dr. Prabhakar is director of the White House Office of Science and Technology Policy (OSTP) and...
View ArticleScience, Serendipity, and Art
Credit: Bryan Bogin and Matthew Steinsaltz, Zachary Levine Lab, Yale University School of Medicine, New Haven, CT Fractals are complex geometric patterns repeated at progressively smaller scales....
View ArticleHow to Feed a Macrophage
Credit: Annalise Bond, Morrissey Lab, University of California, Santa Barbara For Annalise Bond, a graduate student in the lab of Meghan Morrissey, University of California, Santa Barbara (UCSB),...
View ArticleNIH Welcomes Tribal Leaders for Annual Tribal Advisory Committee Meeting
Dr. Karina Walters, Ph.D., director of NIH’s Tribal Health Research Office and I were pleased to welcome Tribal leaders and representatives to the NIH campus on Aug. 16 and 17. These Tribal officials...
View ArticleNew Approach to ‘Liquid Biopsy’ Relies on Repetitive RNA in the Bloodstream
Researchers have identified segments of noncoding RNA circulating in the blood that are early signs of cancer. Credit: Modified from Adobe Stock/ Andrey Popov; Donny Bliss, NIH It’s always best to...
View ArticleRice-Sized Device Tests Brain Tumor’s Drug Responses During Surgery
A device implanted into a tumor during surgery delivers tiny doses of up to 20 drugs to determine each treatment’s effects. Credit: Donny Bliss, NIH Scientists have made remarkable progress in...
View ArticleResearch!America’s National Health Research Forum
On Sept. 20, 2023, I attended Research!America’s National Health Research Forum held at George Washington University in Washington, D.C. Here I am pictured with Mary Woolley (right), President and CEO...
View ArticleRevolutionizing Technology to Treat Genetic Diseases: The NIH TARGETED Challenge
Recent scientific advances in the field of genome editing, which enables precise modifications to DNA, have greatly increased the potential to treat genetic diseases. Despite revolutionary progress in...
View ArticleWords Matter, Actions Have Impact: Updating the NIH Mission Statement
Credit: Donny Bliss, NIH I’ve previously written and spoken about how diverse perspectives are essential to innovation and scientific advancement.1 Scientists and experts with different backgrounds...
View ArticlePain Circuit Discovery in the Brain Suggests Promising Alternative to Opioid...
A pain signal (red) is sent to a neuron in the brain. Researchers have identified a novel anti-pain pathway (blue) that works differently from opioids. Medicines activating this pathway could deliver...
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