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Encouraging First-in-Human Results for a Promising HIV Vaccine

Researchers used a customized nanoparticle (top left) to learn more about guiding the immune system to mount a desired robust response, the type needed for an effective HIV vaccine. Credit: Donny...

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Mapping Immune Cell “Neighborhoods” in Psoriasis to Understand its Course

Researchers mapped immune cell “neighborhoods” in the skin of people with psoriasis compared to the healthy skin of people without psoriasis to learn more about the disease course and why it comes...

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Immune Resilience is Key to a Long and Healthy Life

Caption: A new measure of immunity called immune resilience is helping researchers find clues as to why some people remain healthier even in the face of varied inflammatory stressors. Credit: Modified...

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Changes in Human Microbiome Precede Alzheimer’s Cognitive Declines

Caption: The human gut teems with bacteria and other microbes. They contribute to our health but also influence our susceptibility to certain diseases, including Alzheimer’s disease. Credit: Donny...

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Plans for New Cancer Center in Kansas

It was a pleasure to be in Kansas City and join U. S. Senator Jerry Moran of Kansas to celebrate progress toward the construction of a new building for the University of Kansas Cancer Center. The...

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Visit the New NIH Virtual Tour

Happy Fourth of July! Before everyone heads out to celebrate the holiday with their family and friends, I want to share this brief video with you. It’s an introduction to the brand-new NIH Virtual...

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Understanding Causes of Devastating Neurodegenerative Condition Affecting...

Researchers studied the lack of functional CLN3 protein, which underlies Batten disease. They found lack of the protein leads to a breakdown of the M6PR receptor (green) in the lysosomes and...

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Cryo-EM Scores Again

Caption: Researchers recently published the near-atomic structure of the neuronal pore CALHMI. Credit: Donny Bliss, NIH Human neurons are long, spindly structures, but if you could zoom in on their...

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3D Animation Captures Viral Infection in Action

With the summer holiday season now in full swing, the blog will also swing into its annual August series. For most of the month, I will share with you just a small sampling of the colorful videos and...

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How Neurons Make Connections

Credit: Emily Heckman, Doe Lab, University of Oregon, Eugene For many people, they are tiny pests. These fruit flies that sometimes hover over a bowl of peaches or a bunch of bananas. But for a...

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NIH Welcomes Visitors from OSTP

It was my pleasure to welcome Arati Prabhakar (2nd from right) during her visit to NIH on August 3. Dr. Prabhakar is director of the White House Office of Science and Technology Policy (OSTP) and...

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Science, Serendipity, and Art

Credit: Bryan Bogin and Matthew Steinsaltz, Zachary Levine Lab, Yale University School of Medicine, New Haven, CT Fractals are complex geometric patterns repeated at progressively smaller scales....

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How to Feed a Macrophage

Credit: Annalise Bond, Morrissey Lab, University of California, Santa Barbara For Annalise Bond, a graduate student in the lab of Meghan Morrissey, University of California, Santa Barbara (UCSB),...

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NIH Welcomes Tribal Leaders for Annual Tribal Advisory Committee Meeting

Dr. Karina Walters, Ph.D., director of NIH’s Tribal Health Research Office and I were pleased to welcome Tribal leaders and representatives to the NIH campus on Aug. 16 and 17. These Tribal officials...

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New Approach to ‘Liquid Biopsy’ Relies on Repetitive RNA in the Bloodstream

Researchers have identified segments of noncoding RNA circulating in the blood that are early signs of cancer. Credit: Modified from Adobe Stock/ Andrey Popov; Donny Bliss, NIH It’s always best to...

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Rice-Sized Device Tests Brain Tumor’s Drug Responses During Surgery

A device implanted into a tumor during surgery delivers tiny doses of up to 20 drugs to determine each treatment’s effects. Credit: Donny Bliss, NIH Scientists have made remarkable progress in...

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Research!America’s National Health Research Forum

On Sept. 20, 2023, I attended Research!America’s National Health Research Forum held at George Washington University in Washington, D.C. Here I am pictured with Mary Woolley (right), President and CEO...

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Revolutionizing Technology to Treat Genetic Diseases: The NIH TARGETED Challenge

Recent scientific advances in the field of genome editing, which enables precise modifications to DNA, have greatly increased the potential to treat genetic diseases. Despite revolutionary progress in...

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Words Matter, Actions Have Impact: Updating the NIH Mission Statement

Credit: Donny Bliss, NIH I’ve previously written and spoken about how diverse perspectives are essential to innovation and scientific advancement.1 Scientists and experts with different backgrounds...

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Pain Circuit Discovery in the Brain Suggests Promising Alternative to Opioid...

A pain signal (red) is sent to a neuron in the brain. Researchers have identified a novel anti-pain pathway (blue) that works differently from opioids. Medicines activating this pathway could deliver...

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