Clik here to view.
Taking a Deep Dive into the Alzheimer’s Brain in Search of Understanding and...
Researchers characterized gene activity at the single-cell level in more than 2 million cells from brain tissue. The findings detailed the molecular drivers of Alzheimer’s disease and which cell types...
View ArticleClik here to view.
Persistence Pays Off: Recognizing Katalin Karikó and Drew Weissman, the 2023...
Karikó and Weissman discovered how to slightly modify mRNA to avoid an inflammatory response making the mRNA vaccines possible. Credit: Donny Bliss/NIH Last week, biochemist Katalin Karikó and...
View ArticleClik here to view.
Can Bioprinted Skin Substitutes Replace Traditional Grafts for Treating Burn...
Artificial skin is printed by layering specific cell mixtures to mimic human skin: epidermis (top), dermis (middle) and hypodermis (bottom). Credit: Donny Bliss/NIH Each year in the U.S., more than...
View ArticleClik here to view.
Brain Atlas Paves the Way for New Understanding of How the Brain Functions
Neurons. Credit: Leterrier, NeuroCyto Lab, INP, Marseille, France When NIH launched The BRAIN Initiative® a decade ago, one of many ambitious goals was to develop innovative technologies for profiling...
View ArticleClik here to view.
How Double-Stranded RNA Protects the Brain Against Infection While Making...
A neuron (white) with double-stranded RNA (yellow). Credit: Donny Bliss, NIH. When you get a run-of-the-mill viral infection, after a few days of symptoms your immune system typically fends off the...
View ArticleClik here to view.
First Lady Dr. Jill Biden Visits NIH
It was an honor to welcome the First Lady of the United States Dr. Jill Biden and Ms. Jodie Haydon of Australia to NIH last week. We shared NIH’s progress in pediatric cancer research during a visit...
View ArticleClik here to view.
Senator Ben Cardin Visits NIH
I was pleased to welcome Senator Ben Cardin to NIH last week for a lab tour and an update on NIH’s progress in minority health research. To my left is Dr. Tara Schwetz, NIH Acting Principal Deputy...
View ArticleClik here to view.
Reflecting on Two Years of Discovery and Looking Ahead to New NIH Leadership
Dr. Larry Tabak in his office at the National Institutes of Health. Credit: NIH As I transition from my role as the Acting NIH Director, I’d like to thank you, the readers, for visiting the NIH...
View ArticleClik here to view.
Metabolomics: A New Approach to Understanding Glaucoma
Patients with high levels of triglycerides and diglycerides in blood samples were more likely to develop glaucoma. Credit Donny Bliss/NIH Glaucoma remains one of the most common causes of vision loss...
View ArticleClik here to view.
The Amazing Brain: Turning Conventional Wisdom on Brain Anatomy on its Head
Credit: Silas Busch, The University of Chicago Silas Busch at the University of Chicago captured this slightly eerie scene, noting it reminded him of people shuffling through the dark of night. What...
View ArticleExperiencing the Neural Symphony Underlying Memory through a Blend of Science...
Ever wonder how you’re able to remember life events that happened days, months, or even years ago? You have your hippocampus to thank. This essential area in the brain relies on intense and highly...
View ArticleClik here to view.
Turning Discoveries into Health for All
Health and Human Services Secretary Xavier Becerra (left) swears in Monica M. Bertagnolli, M.D., (right) as the 17th Director of the National Institutes of Health. Dr. Bertagnolli’s husband, Alex...
View ArticleClik here to view.
Uncovering Disease-Driving Events that Lead to Type 2 Diabetes
Researchers found lower levels of the protein RFX6 led to beta cells in the pancreas releasing less insulin. Lower RFX6 levels also led to structural changes in the DNA, specifically in sites that...
View ArticleClik here to view.
A New Target to Improve the Health and Lives of Childhood Cancer Survivors:...
Researchers found that prediabetes and diabetes are highly prevalent in survivors of childhood cancer. Credit Donny Bliss/NIH. Modified from SB Dixon, et al. Before joining NIH, I conducted research...
View ArticleClik here to view.
New Findings in Football Players May Aid the Future Diagnosis and Study of...
A new study found injuries to the white matter in football players who had experienced repetitive head impacts. Credit: Adobe Stock/Guido Amrein/merydolla Repeated hits to the head—whether from...
View ArticleClik here to view.
Findings in Tuberculosis Immunity Point Toward New Approaches to Treatment...
Researchers gave one group of mice a contained infection with the bacteria that causes TB and immunized another. Later when exposed to TB, macrophages from each group turned on two separate...
View ArticleClik here to view.
What’s Behind that Morning Migraine? Community-Based Study Points to...
Credit: Adobe Stock/nenetus Headaches are the most common form of pain and a major reason people miss work or school. Recurrent attacks of migraine headaches can be especially debilitating, involving...
View ArticleClik here to view.
Understanding Childbirth Through a Single-Cell Atlas of the Placenta
A person in labor. Credit: Adobe/Prostock-studio While every birth story is unique, many parents would agree that going into labor is an unpredictable process. Although most pregnancies last about 40...
View ArticleClik here to view.
Study Offers New Clues to Why Most People with Autoimmune Diseases Are Women
Xist molecules shut down one of two female X chromosomes to avoid toxic protein levels, but they may also play a role in triggering autoimmune diseases. Credit: Donny Bliss/NIH As many as 50 million...
View ArticleClik here to view.
A Potential New Way to Prevent Noise-Induced Hearing Loss: Trapping Excess Zinc
Zinc in the inner ear is concentrated in stereocilia essential for hearing, but a new study finds that loud sounds cause damaging dysregulation of the essential mineral that can lead to noise-induced...
View Article